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Secondary Antibodies and Controls

Why Choose BBI Solutions Monoclonal Antibodies?

At BBI Solutions, we offer a diverse range of monoclonal antibodies to ensure the reliability and performance of your diagnostic assays.

Specialised subset of 10 monoclonal anti-human secondary antibodies for broad recognition of human immunoglobulins. Control antibodies for the detection of Histidine-tagged and Pegylated proteins with some of the most cost-effective products in the marketplace. Strong security of supply: BBI’s panel of anti-human secondary antibodies, anti-His tag antibody, and anti-PEG antibodies are manufactured and controlled by BBI Solutions at our cGMP* facility in Maine, USA

Trusted by assay developers wordwide

BBI Solutions’ monoclonal antibodies are renowned as sensitive, cost-efficient products for assay developers, manufacturers, and researchers worldwide. They are available in both small and bulk quantities depending on your individual needs.

Please contact our Customer Services Team directly to discuss your requirements on tel:+44 (0) 1495 363000 or alternatively you can submit an enquiry here.

*21 CFR Part 820, For research and In Vitro diagnostic use.

Anti-human Secondary Antibodies - Unconjugated

Product description	Product code
Human IgA Monoclonal Antibody	MAB217P
Human Immunoglobulin ε (hu-IgE) Monoclonal Antibody	MAB114P
Human IgG Heavy Chain Monoclonal Antibody	MAB142P
Monoclonal to Human IgG1 Monoclonal Antibody	MAB146P
Human IgG2 Monoclonal Antibody	MAB220P
Human IgG3 Monoclonal Antibody	MAB221P
Human IgG4 Fc Monoclonal Antibody	MAB154P
Human IgG Fc Monoclonal Antibody	MAB218P
Human IgM Monoclonal Antibody	MAB216P
Human Ig Kappa Light Chain Monoclonal Antibody	MAB199P
Human Ig Lambda Light Chain Monoclonal Antibody	MAB219P

Custom Monoclonal Antibody Development

BBI Solutions provides custom monoclonal antibody development services, covering the design of a custom strategy and project plan all the way through ...

Polyclonal Antibody Development

Partner with our expert antibody team for custom polyclonal antibody development for any application. All polyclonal antibody development projects are...

Anti-Idiotypic Antibody Development

BBI Solutions has extensive experience in developing highly sensitive and specific anti-idiotypic antibodies to support the development of monoclonal ...

Gold Conjugation Services

BBI Solutions has over 30-years of experience in the development of reliable lateral flow assays, and one of the most important factors is the quality...

Antibodies FAQs

Our team are here to help! If you can’t find the answer you are looking for contact us.

Download as PDF

Antibodies are a critical component of the defense arsenal assisting with identifying, capturing, and removing potential threats as well as protecting against future invasions. Antibodies are gammaglobulin proteins, predominantly referred to as immunoglobulins (Ig). A monomeric antibody is composed of two heavy chains and two light chains covalently linked together through disulfide bonds to generate a Y-shaped structure. This Y-shaped structure provides a bifunctional capacity: 1) antigen-binding through the Fab (antigen binding fragment), and 2) interaction with immune cells and proteins (fragment crystallizable or Fc) to initiate and regulate host defence mechanisms.

Polyclonal antibodies refer to a mixture of immunoglobulin molecules that are secreted against a particular antigen. They interact with different epitopes on the same antigen and their manufacture does not require the use of hydbridomas. Monoclonal antibodies refer to a homogenous population of antibodies that are produced by a single clone of plasma B cells. They interact with a particular epitope on the antigen and their
manufacture requires the use of a hybridoma cell line.

This varies between products, please consult the example Certificate of Analysis (found in the ‘Technical Documents’ section of the product page) for this information.

Yes, we manufacture many of our own products at our 2 manufacturing sites in Maine, USA and Porton Down, UK. All sites are ISO13485 certified.

BBI Solutions offers a growing portfolio of performance proven antibodies. With our in-house custom antibody expertise, customers can rely on BBI to be a trusted partner in antibody support, from secure supply, to matched pair recommendations, and trouble shooting performance. Custom manufacturing lots and conjugation services are also value-added services available for most of our antibodies to suit your assay development needs.

A matched antibody pair consists of two antibodies, a capture and a detection antibody. In a matched pair, each antibody is specific for a different and non-interfering epitope of the antigen.

Hybridoma.

Rabbit, Goat and Sheep.

Roller bottle for lot sizes up to 1gram. Hollow fibre continuous perfusion system for lot sizes greater than 1 gram.

4-6 months for a monoclonal antibody and 3-4 months for a polyclonal.

A discussion with a service team member will be necessary regarding this, however monoclonal development projects start at $20k and up.

As this is a complex subject, a separate FAQ has been written for it and can be found on the Antibody Development services page.