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Apo Transferrin
$260.96
SKU
T100-5
Why choose BBI?
+ Over 98% purity
+ Batch-to-batch consistency
+ Research-grade prices
Mammalian cell culture in a serum free medium requires an iron transporter such as transferrin. Human transferrin is a 77 kDa beta-glycoprotein with a range of phenotypes based upon the number of sialic acid residues. Each molecule of transferrin specifically binds two Fe3+ molecules.
The iron content can be adjusted to give near 100% saturation to yield holo-transferrin (Iron 1200-1600 ug/gm) or depleted to give near zero iron bound to yield apo-transferrin (Iron <50ug/gm protein) or the intermediate- sidero-transferrin (Iron 300-1000ug/gm protein).
The secondary role for transferrin in culture media is to bind endogenous metal iron which may cause cell toxicity.
| Abbreviation | APOT |
|---|---|
| Applications | Mammalian Cell Culture |
| CAS Number | 11096-37-0 |
| Disease Area | Plasma Proteins |
| Keywords | human, apo transferrin, transferrin, cell culture |
| Presentation Matrix | Lyophilised |
| Product Category | Cell Culture Reagents |
| Purity/Grade | >98% |
| Recommended Use | Iron binding and transport in cell culture media |
| Shipping Recommendation | Cool pack |
| Source | plasma |
| Storage | 4°C |