Apo Transferrin


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+ Over 98% purity

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Mammalian cell culture in a serum free medium requires an iron transporter such as transferrin. Human transferrin is a 77 kDa beta-glycoprotein with a range of phenotypes based upon the number of sialic acid residues. Each molecule of transferrin specifically binds two Fe3+ molecules.

The iron content can be adjusted to give near 100% saturation to yield holo-transferrin (Iron 1200-1600 ug/gm) or depleted to give near zero iron bound to yield apo-transferrin (Iron <50ug/gm protein) or the intermediate- sidero-transferrin (Iron 300-1000ug/gm protein).

The secondary role for transferrin in culture media is to bind endogenous metal iron which may cause cell toxicity.

More Information
Abbreviation APOT
Applications Mammalian Cell Culture
CAS Number 11096-37-0
Disease Area Plasma Proteins
Keywords human, apo transferrin, transferrin, cell culture
Presentation Matrix Lyophilised
Product Category Cell Culture Reagents
Purity/Grade >98%
Recommended Use

Iron binding and transport in cell culture media

Shipping Recommendation Cool pack
Source plasma
Storage 4°C
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