Enzymes
World-leading Enzymes
Powering your assays for over 70 years, our ISO 13485-certified processes keep every lot of our specialist enzymes pure, stable, and reproducible.
Built on a long legacy of enzyme innovation, we extract and purify native enzymes from microbial, plant and animal sources – as well as developing and manufacturing recombinant forms.
BBI is the world’s largest global primary manufacturer of horseradish peroxidase (HRP) and a leading supplier of glucose oxidase (GO) – powering more than five billion tests each year.
Clinical Chemistry
High-purity oxidases, dehydrogenases and urease keep chemistry assays stable, letting analysers run longer between calibrations and deliver results faster.
Immunoassay Label
Horseradish Peroxidase (HRP) and Alkaline Phosphatase (ALP) from BBI are the top-of-line enzymes for conjugation to antibodies, for your immunoassay needs.
Molecular Biology
Nuclease- and protease-free DNase, RNase, and protease grades protect PCR and NGS runs.
Biosensor
BBI’s trusted glucose oxidases drive over 5 billion assays annually, delivering secure supply for high volume test and device manufacturers, and quick results for consumers.
Heparinase
Recombinant Heparinases I, II, and III deliver consistent heparin cleavage, for low-molecular-weight heparin production and accurate coagulation tests, as well as for glycobiology research and diagnostic devices.
Hyaluronidase
High-purity ovine and bovine hyaluronidase remodel extracellular matrix consistently, accelerating wound-healing and regenerative-medicine studies.
Research
Start with trial packs of catalase, LDH and more – then scale to ISO 13485 bulk, derisking the path from concept to launch with one partner.
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Products & Services
Inside this catalog you’ll find one of the industry’s broadest collections of enzymes, antibodies, antigens, and more – meticulously developed to power world-class diagnostics and keep your pipeline moving.
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Frequently asked questions
Enzymes
Where are your enzymes manufactured?
All core enzymes are produced in our ISO 13485-certified plants in Crumlin (UK) and Cape Town (SA).
How should I store and ship each enzyme?
Different enzymes have different storage and shipping requirements. Check the individual enzymes documentation for exact details. On arrival store ALP at 2–8 °C glycerol solution. Lyophilised GOx, HRP, RNase and Urease keep best desiccated below –15 °C.
Can I extend the best-before date on my enzyme?
Email technicalsupport@bbisolutions.com—many grades qualify for a validated shelf-life extension.
Which applications are BBI enzymes commonly used in?
Biosensors, immunoassays, clinical chemistry and molecular diagnostics are the four most common uses.
What makes your alkaline phosphatase a good ELISA label?
Highest-activity conjugation grade (> 2 000 Gly U mg-¹) with < 10 % activity loss over 48 months – delivering low background and extended incubations.
What purity/activity levels can I expect from horseradish peroxidase?
There are options for multiple grades, including those that deliver ≥ 90 % isozyme C and ~ 280 U mg-¹ activity for clean, rapid conjugation.
Do you supply bulk volumes?
Yes – order anywhere from R&D vials to > 10 000 ku ALP or > 1 000 MU GOx; we pack to order.
What documents ship with each batch?
We operate an ISO13485 quality system. That means a Certificate of Analysis and Safety Data Sheet are available to you.
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IN FOCUS
The world’s largest primary manufacturer of horseradish peroxidase
BBI’s peroxidase offers the widest range of grades on the market, giving you unmatched scale and unparalleled security of supply. We have a range of isozyme and purity options to meet any application requirement.
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ADDING VALUE
Compliance
ISO 13485 certification plus FDA registration and full documentation make every lot audit-ready – speeding global approvals and market entry.
Scalability
Whether you’re testing ideas with 0.1 mg trial packs, or expanding production to 5000L lots, our capacity scales seamlessly with your needs, no costly supplier switch required.
Security
Dual-site manufacturing and global stock buffers secure supply, even during raw-material shortages or demand spikes – so your production timeline stays protected.
Performance
Robust quality controls track every production step, ensuring consistent product performance batch-to-batch – so your assays, devices, and studies run reliably every time.
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IN FOCUS
ISO Certifications
All our enzymes are manufactured at facilities certified to internationally recognised ISO13485 quality management standards – so your diagnostics start with a proven quality backbone. Our ISO27001 certification ensures your data is safeguarded, and we’re now charting a path to ISO 14001 and ISO 45001 to fold sustainability and safety into every batch.
Our certifications
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Still need help? Talk to our team
Our customer service team is on hand to help with any questions you have or support you need.
And if the issue is technical, they’ll bring in our world-leading expert scientists to troubleshoot side-by-side with you and keep your project moving.
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