Polyclonal antibodies refer to a mixture of immunoglobulin molecules that are secreted against a particular antigen. They interact with different epitopes on the same antigen and their manufacture
does not require the use of hydbridomas. Monoclonal antibodies refer to a homogenous population of antibodies that are produced by a single clone of plasma B cells. They interact with a particular epitope on the antigen and their manufacture requires the use of a hybridoma cell line.

This varies between products, please consult the example Certificate of Analysis for this information.

This varies between products, please consult the example Certificate of Analysis for this information.

Yes, we manufacture many of our own products at our 2 manufacturing sites in Maine, USA and Porton Down, UK. All sites are ISO13485 certified.

BBI Solutions offers a growing portfolio of performance proven antibodies. With our in-house custom antibody expertise, customers can rely on BBI to be a trusted partner in antibody support, from secure
supply, to matched pair recommendations, and trouble shooting performance. Custom manufacturing lots and conjugation services are also value-added services available for most of our antibodies to suit your assay development needs.

A matched antibody pair consists of two antibodies, a capture and a detection antibody. In a matched pair, each antibody is specific for a different and non-interfering epitope of the antigen.

Hybridoma.

Rabbit, Goat and Sheep.

Roller bottle for lot sizes up to 1gram. Hollow fibre continuous perfusion system for lot sizes greater than 1 gram.

4-6 months for a monoclonal antibody and 3-4 months for a polyclonal.

A discussion with a service team member will be necessary regarding this, however monoclonal development projects start at $20k and up.

As this is a complex subject, a separate FAQ has been written for it and can be found here http://www.bbisolutions.com/en/services/monoclonal-development