Antigens
World-leading Antigens from BBI.
Native or recombinant, every antigen is produced under our ISO 13485 system – ethically sourced, with batch-to-batch consistency, and ready to plug straight into your immunoassay.
Over decades, we’ve built one of the industry’s broadest antigen portfolios – covering critical markers in autoimmunity, diabetes, allergy, cardiac, tumour, hormonal, renal, and more – so you can source every critical target from one ISO 13485-certified, global partner.
We don’t just deliver quality; we scale it. Our industrial-scale production runs (including lots exceeding 100g and purities reaching beyond 99%) use formulations validated for up to five-year stability and are recovery-tested for lot-to-lot reproducibility.
Allergy
Purified allergen components – food, grass, and tree – isolated or recombinantly expressed, purified using BBI’s specialized (purification) technologies and extensively characterized.
Plasma Proteins
For four decades we’ve refined plasma proteins from rigorously screened donors, supplying highly or part-purified lots – batch-recorded, shelf-stable, assay-verified – supporting calibrators, controls, reference matrices, & cell-culture formulations
Infectious Disease
Target viral & bacterial markers with confidence. Our recombinant antigens are purified using specialized methods and are often cross-checked against patient samples for proven performance.
Hormones
Purified hCG, prolactin, SHBG, and more – expressed in Pichia or plasma-derived – deliver tight calibration curves, letting fertility and endocrine assays run with fewer repeats.
Diabetes & Renal
Safety-screened native or recombinant HbA1c, cystatin C, NGAL, RBP, and specialty renal biomarkers – batch-recorded, shelf-life-optimized, in highly or part-purified grades – ready for precise diabetes and renal assays.
Tumor Marker
Native and recombinant AFP, PSA, CA15-3, CYFRA 21-1, and more, reach high purities with stability validated up to five years, underpinning trustworthy oncology assays.
Cardiac & Vascular
Safety-screened native or recombinant troponin, myoglobin, NT-proBNP and D-dimer arrive batch-recorded, shelf-life optimized and available in highly or part-purified grades – scheduled to meet your forecasted timelines.
Autoimmune & Inflammation
Comprehensive panel of highly purified AI markers for serology assays, carefully engineered and tested using patient and healthy samples. Inflammation markers for calibrator & control development such as CRP – recovery tested and highly purified.
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Products & Services
Inside this catalog you’ll find one of the industry’s broadest collections of enzymes, antibodies, antigens, and more – meticulously developed to power world-class diagnostics and keep your pipeline moving.
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Frequently asked questions
Antigens
What are antigens and how are they used?
BBI antigens are purified human proteins—either native or recombinant—that serve as critical reagents for making in-vitro-diagnostic (IVD) calibrators and quality-control materials; in some cases they also provide specific biological functionality for research or cell-based assays.
What is the source material for your antigens?
Depending on the product, antigens are produced recombinantly in prokaryotic or eukaryotic systems, purified from consented human tissues or body fluids, or harvested from well-characterised human cell lines.
Where are the antigens manufactured and purified?
Manufacturing takes place at BBI’s ISO 13485-certified facilities in Crumlin, UK, and Freiburg, Germany, both of which operate strict quality-management systems and traceable batch records.
How does BBI guarantee lot-to-lot consistency?
Every production lot follows documented SOPs, is subjected to biochemical and immunological testing, and must meet tight release specifications before it leaves QC, ensuring reproducible performance in your assay.
How should I handle the material when it arrives?
Store at the temperature specified on the CoA.
How can I obtain pricing?
Pricing is volume-dependent; you can check our online shop or request a formal quotation from your account manager or contact customer services.
How do I check stock availability or secure future supply?
Your account manager can provide current inventory levels, arrange reservations, and help integrate your six-month forecasts into our production planning. You can also contact us or use our online shop if you don’t have an account manager yet.
What is the process if I have a complaint or quality concern?
All complaints should be sent to Complaints@bbisolutions.com. All issues are investigated under BBI’s ISO 13485 quality-management system, and we will work with you to reach a satisfactory resolution.
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ISO Certifications
All our antigens are manufactured at facilities certified to internationally recognised ISO13485 quality management standards – so your diagnostics start with a proven quality backbone. Our ISO27001 certification ensures your data is safeguarded, and we’re now charting a path to ISO 14001 and ISO 45001 to fold sustainability and safety into every batch.
ADDING VALUE
Performance
High-purity antigen grades exceeding 95 % are recovery-tested for lot-to-lot consistency, giving assays sharp signal-to-noise and rapid, confident diagnostic calls.
Scalability
From pilot-scale milligrams to hundred-gram batches, our ISO 13485 bioprocesses and global logistics flex with your forecasts, ensuring on-spec antigen supply worldwide.
Compliance
ISO 13485 certification plus FDA registration and full documentation make every lot audit-ready – speeding global approvals and market entry.
Security
Global primary manufacturing and secure supply chains ensure security of supply, so your production timeline stays protected.
GET IN TOUCH
Still need help? Talk to our team
Our customer service team is on hand to help with any questions you have or support you need.
And if the issue is technical, they’ll bring in our world-leading expert scientists to troubleshoot side-by-side with you and keep your project moving.
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