Custom reagent preparation to support IVD manufacturers
When a reliable reagent source is hard to find
Our scientists are problem solvers
We’re here to help with specific challenges to your IVD assay development with programs to develop custom:
- Sourcing and processing of reagents
- Purification / activity specifications
- Pack sizes / dispense volumes
- Formulation (preservatives, buffers, lyophilization)
- Labelling / OEM supply
Our team screens genes, fine-tunes fermentations from pilot to production scale, and purifies at up to 5,000L batches, delivering validated, assay-ready biomolecules with secure, repeatable supply.
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Ready to assist you across a broad range of reagent development requirements, diagnostic reagents, biological materials and processes
We also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn MoreWe also develop and scale production of monoclonal and polyclonal antibodies
Learn More
Aligning Performance, Process Design & Reliable Long-Term Supply
Working Collaboratively
We understand that custom reagent development is not just changing a product, It’s a building a partnership
- Understand the application
Project requirements, assay context, platform needs, performance goals and commercial priorities
- Define the development pathway Scientific, analytical and technical teams assess the best route success.
- Optimise and evaluate
Project specific formulation, expression, modification, depletion, conjugation or process optimization
- Align specifications and verify performance Analytical testing, specification alignment and reproducibility checks.
- Support reliable supply. Technical transfer, consistent project output, quality systems and ongoing supply planning
Designed for Assay Developers
To international quality frameworks
Custom reagent development is only valuable if it can be delivered reliably.
BBI supports clients with quality systems, technical transfer capability and process design built to support long-term diagnostic supply and performance verification to recognised international quality frameworks.
Service Spotlight
Gold Conjugation
Put over 30 years of gold nanoparticle know-how behind your assay.
We conjugate antibodies, antigens, aptamers, oligos or biotinylated proteins to high-grade BBI gold, using your reagents or sourcing them on your behalf.
Our proprietary protocol focuses on three absolutes: specificity, sensitivity, and lot-to-lot reproducibility.
From first call to finished vial, our scientists work side-by-side with your team to build a conjugate that performs exactly as your test demands.
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Service Spotlight
Antigen Modification
As a primary manufacturer BBI can support a range of adaptations of current products or source material from a broad range of human tissues and fluids from its extensive worldwide supply chain.
Common modifications include modifications to:
- Dispensing volumes
- Concentrations
- Formulations
- Purifications
- Analytical testing methodologies
As a UK government human tissue authority licenced site, native antigen products are sourced from ethical, stable raw material suppliers.
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Service Spotlight
Enzyme Customization
Specialists in sourcing and extraction of animal and plant products we have extensive experience in sourcing raw materials worldwide.
Broad customization capabilities
- Salt/solvent fractionation
- Chromatography
- Crystallization
- Freeze drying optimization
- Ultrafiltration
- Quality control
- in-process analysis and monitoring
- development of assay/test procedures
- Custom Packaging
Service Spotlight
Buffer & Formulation Optimization
Sometimes your test needs an adjusted reagent formulation. Whether it’s in response to a change in reagent risk categorization or to avoid the potential for cross reaction BBI have the capability to remove or source alternatives components such as stabilizers, preservatives or detergent to ensure the final formulation is optimal for your test.
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Service Spotlight
Stability Enhancement
Need additional raw material stability?
BBI can reformulate for additional stability using a range of stabilization strategies and perform accelerated and real-time stability assessments to support your development or manufacturing process.
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Service Spotlight
Depleted Serum Development
As a primary manufacturer BBI can support a range of adaptations of serum or plasma products and source material from its extensive worldwide supply chain.
We use affinity binding and expertly selected antibodies to remove specific proteins in a process scalable up to 30 litres.
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Service Spotlight
Custom Sourcing
As a HTA compliant manufacturer BBI can leverage its broad network of collaborators and suppliers to source raw materials. Consolidate your supply with BBI.
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